i just used my room mates disc to install a game on my computer and i downloaded the 1st cd online so i wouldnt have to borrow it from my roomy all the time. ive mounted the iso on a clone drive but when i open the game through that way it only gives me the option to install(the play game button is grayed out) and if i go through the short cut on my desktop that was created when i installed the game it says i need to insert a cd into drive D. so how can i make the game choose the clone drive i made or is there another way i can make it work?

Best bet is to download a NO-CD/DVD crack. You can get one for most games at www.gamecopyworld.com.

Otherwise, maybe reinstall from the clone drive?

Ya if you install via disk it will look for the game in D: drive if you install from say Daemon tools virtual drive it will look for disk there. But do as Salamandastron done